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Nature Medicine Publishes Updated Preliminary Phase 1 Data From Elicio Therapeutics' AMPLIFY-201 Phase 1 Solid Tumor Study Of ELI-002

Benzinga

By Jeremy Golden, Benzinga Colorectal cancer (CRC) and pancreatic ductal adenocarcinoma (PDAC) are the second and third leading causes of cancer death, respectively. Pancreatic and colorectal cancers are often Kirsten rat sarcoma (KRAS) mutated and are incurable when tumor DNA or protein persists or recurs after curative intent therapy. KRAS mutations are among the most prevalent human cancers. For these cancers, caused by a mutation of the KRAS gene, clinical-stage biotechnology company Elicio Therapeutics Inc. (NASDAQ: ELTX) is developing a pipeline of novel immunotherapies for treatment. Founded in 2011, Elicio Therapeutics has developed an innovative pipeline of cancer immunotherapies addressing critical unmet needs. Three vaccine candidates are currently in Elicio Therapeutics’ pipeline: ELI-002, ELI-007 and ELI-008. Elicio’s lead clinical program, ELI-002, is a structurally novel investigational AMP therapeutic immunotherapy targeting mutant KRAS-driven cancers. It was designed to stimulate an immune response against the seven KRAS mutations driving 25% of solid tumors. ELI-002 2P has been studied in a phase 1 dose-escalation study in patients with high relapse risk mKRAS-driven solid tumors, following surgery and chemotherapy. After early findings from AMPLIFY-201 were released, ELI-002 was the subject of a publication in Nature Medicine. The paper — “ Lymph Node Targeted, mKRAS-specific Amphiphile Vaccine in Pancreatic and Colorectal Cancer: The phase 1 AMPLIFY-201 Trial ” — details expanded and updated results that point to the power of Elicio Therapeutics’ use of precision vaccines, immunomodulators and cell-based therapies to assemble cancer-killing immune responses against solid tumors. Originally presented at the 2023 American Society of Clinical Oncology (ASCO) Annual Meeting and the 2023 AACR Special Conference on Pancreatic Cancer, the data detailed in the publication is as of September 6, 2023. It is based on 25 patients with solid tumors (20 pancreatic, 5 colorectal) who were positive for minimal residual mKRAS disease after locoregional treatment. “When tumor DNA or protein persists or recurs after treatment, patients with pancreatic and colorectal cancers are unfortunately not left with many options and are often incurable,” said study author Shubham Pant, M.D., Associate Professor of Gastrointestinal Medical Oncology at The University of Texas MD Anderson Cancer Center. “These are promising early findings from the AMPLIFY-201 study with follow up ongoing. Most patients reduced their tumor biomarkers with some having complete clearance following treatment with ELI-002.” “The lymph node-targeted cancer vaccine candidate induced direct ex vivo mKRAS-specific T cell responses in 84% of patients, with 59% of patients demonstrating a response with two key types of T cells: helper cells and killer cells,” according to Christopher Haqq, M.D., Ph.D., Elicio’s Executive Vice President, Head of Research and Development, and Chief Medical Officer. “Past studies have not produced this large a fraction of patient response, this high a magnitude of a response or the expansion of both key populations of T cells,” he said. “Importantly, these T cell responses were specific to tumor-driver mutant KRAS neoantigens, correlated with reduced risk of relapse and we saw a pool of memory T cells form that we believe hold promise to confer long-term protection,” Haqq said. “We look forward to progressing ELI-002 into a randomized phase 2 trial as a monotherapy for patients with PDAC.” ELI-002 7P is currently being studied in AMPLIFY-7P, a phase 1/2 trial in patients with high relapse risk mKRAS-driven solid tumors. The ELI-002 7P formulation is designed to provide immune response coverage against seven of the most common KRAS mutations, thereby increasing the potential patient population for ELI-002 and possibly reducing the chance of bypass resistance mechanisms. Benzinga is a leading financial media and data provider, known for delivering accurate, timely, and actionable financial information to empower investors and traders. This post contains sponsored content. This content is for informational purposes only and is not intended to be investing advice. Contact Details Benzinga +1 877-440-9464 info@benzinga.com Company Website http://www.benzinga.com

January 30, 2024 08:10 AM Eastern Standard Time

Sprott’s Energy Transition ETFs: A Look Back And A Look Ahead

Benzinga

By Austin DeNoce, Benzinga Sprott is a leader in precious metals and energy transition investments, making strides in the evolving move to cleaner energy. With the launch of five new Exchange Traded Funds (ETFs) in the first quarter of 2023, Sprott has expanded its offerings for investors to find pure-play exposure to the critical minerals essential for cleaner energy production and storage. Overview Of The Sprott Energy Transition ETFs The year 2023 has exhibited a pivotal shift in the energy sector, with increasing global mandates for reduced carbon emissions increasingly driving capital and interest toward viable energy alternatives. Sprott's Energy Transition ETFs – SETM, LITP, URNM, URNJ, COPJ and NIKL – provide a targeted approach for investment in miners of vital minerals like lithium, uranium, copper, nickel and others pivotal in the broader energy transition. John Ciampaglia, CEO of Sprott Asset Management, emphasizes the critical role of these minerals in meeting the escalating demand for low-carbon energy solutions. He also highlights the existing gap between supply and demand, largely due to historical underinvestment. This scenario presents a unique opportunity for mining companies in this domain, poised to capitalize on the potential impending surge in investment. Market Trends With each of these new ETFs, Sprott aims to provide investors the opportunity to capitalize on the potentially sizable growth of the low-carbon energy markets throughout this decade. In 2023, the global lithium market was roughly $8.2 billion, but it is estimated to see a compound annual growth rate (CAGR) of 12.8% from 2024 all the way to 2030. Meanwhile, the uranium market is expected to grow at a CAGR of 7.06% up to 2027, while copper is estimated to see a CAGR of 4.21% through 2029. Market predictions are always subject to the possibility of error, especially when forecasting far into the future, but there are only a handful of minerals capable of filling the void left by fossil fuels. The extent to which the broader energy transition materializes is to be seen, but markets will have to rely heavily on one or all of the viable alternatives if we are to make any meaningful progress toward decarbonization. Individual ETF Focus Each ETF in Sprott's portfolio offers a unique investment opportunity within the energy sector: SETM: Focused on a broad range of critical minerals essential in the transition to clean energy. LITP: Concentrated on the lithium industry critical to meeting increasing electric vehicle (EV) demand, including lithium producers, developers and explorers. URNM: Tracks the performance of companies that devote 50%+ of assets to the uranium mining industry. URNJ: Targeted at small-cap uranium miners integral to the nuclear energy sector. COPJ: Centered on small-cap miners in the copper industry, which are essential for electrical infrastructure across industries. NIKL: Tracks the performance of a selection of securities in the nickel industry, including producers, developers and explorers. 2023 Performance Analysis Despite a troubling year battling the steep rise in interest rates, the long-term outlook of Sprott’s energy ETFs remains focused on the vital role of these minerals in the burgeoning low-carbon energy sector, particularly in EVs. “As the global energy transformation advances, a new commodity supercycle is emerging.” Sprott’s Jacob White CFA, and Paul Wong, CFA and Market Strategist said. The year-to-date performances of Sprott’s Energy Transition ETFs are as follows: SETM: -11.60% LITP: -35.77% URNM: 56.88% URNJ: 20.05% COPJ: -7.18% NIKL: -18.43% Looking Ahead to 2024 As we approach 2024, the market outlook remains cautiously optimistic. The potential growth in the energy transition materials market is closely tied to global policies and economic factors. While challenges are inevitable, the potential opportunities in this sector remain substantial, especially given the increasing focus on sustainable energy solutions and government-driven mandates and incentives such as those outlined in the Inflation Reduction Act. “Global metal consumption is forecasted to rise in 2024, fueled by the burgeoning renewable energy sector and the EV market. This "green boom" is expected to offset sluggishness in more traditional industries.” Sprott’s Jacob White CFA, and Paul Wong, CFA and Market Strategist said. The Energy Evolution Investing in Sprott's energy transition ETFs offers a strategic pathway for investors to align with the global shift toward sustainable energy through a variety of commodity subsectors. While the investment landscape in each sector is subject to its supply and demand dynamics, the underlying trend toward cleaner energy solutions underscores the potential for growth and the importance of these investments in a diversified portfolio. Benzinga is a leading financial media and data provider, known for delivering accurate, timely, and actionable financial information to empower investors and traders. This post contains sponsored content. This content is for informational purposes only and not intended to be investing advice. Contact Details Benzinga +1 877-440-9464 info@benzinga.com Company Website http://www.benzinga.com

January 30, 2024 08:05 AM Eastern Standard Time

These Two Assets Historically Limited To Ultra-Wealthy Investors Have Seen Triple Digit Returns Over The Past Decade – Vint Expands Access With Latest Fund

Benzinga

By Meg Flippin, Benzinga Invest in long-term appreciation opportunities through fine wine and rare whisky here. Great taste and a nice buzz aren’t the only things you can toast when it comes to fine wine and rare whisky. There’s also the potential for a nice return on them as asset classes. Over the past few years, fine wine and rare whisky prices have witnessed growth as investors turn to them as a way to diversify and hedge against inflation. The Knight Frank Fine Wine Icons Index (KFFWII), which tracks a sector of wines that represent the fine wine investment market, is up 149% over the past ten years. Meanwhile, the Knight Frank Rare Whisky index, which tracks the auction results of a basket of rare Scottish single malts, is up 586% over the past decade. Leveling The Playing Field Despite the returns, getting access to this multi-billion dollar market historically favored by the ultra-wealthy can be difficult for regular investors. Historically, industry insiders and members of hard-to-get-on allocation lists are the ones who get to take part in this alternative investment opportunity. That’s changing thanks to companies like Vint. The platform for wine and spirits collection investing is leveling the playing field through its equity products and marketplace, giving investors and consumers access to fine wine and rare spirits with the potential for long-term appreciation. Learn more about the fine wines and whiskies at Vint’s marketplace. Vint’s innovation aims to capitalize on emerging trends while improving access to these investment opportunities. Demand for the top French wines is growing at the same time that access to them is proving difficult. That has created what the company says is a significant pricing delta among the U.S., Europe and Asia for many of these assets. Through its funds, Vint aims to give investors an efficient and tax-advantaged investment product to capitalize on this arbitrage. The company uses collected investor capital to buy physical bottles and cases of wine and whisky in one region and sell them in another. Once an asset sale is made, Vint reinvests the funds and any gains into new purchases. Best Of Both Worlds With Vint’s New Fund To encapsulate that opportunity in both the wine and whisky markets, Vint recently launched the Vint Futures and Casks I (VV-FC1) fund. Open to accredited investors with a minimum investment of $2,500, the goal of the fund is to give investors a blended approach to investing in wine and spirits and capture the quality potential from recent vintages of top wine from Bordeaux and other regions while also leveraging the strong demand and trading activity of spirits casks. What drives prices for spirits casks and wine futures is the scarcity. When producers limit the release, the market value tends to soar. As it ages and is consumed, quality and scarcity increase, driving the value of the wine or whisky higher. This gives investors the potential for long-term appreciation. Over the years spirits and wine have proven to be a solid investment, outperforming the broader markets. A popular way to gain exposure to fine wine and rare whisky is through wine and spirits futures. These enable investors to invest in the assets at their release price, providing the potential for significant upside as the price increases. Bordeaux wines, known for their aging potential are one example of a wine that could provide long-term appreciation, but there are others, as well. Cask investing affords investors the same opportunity. The only difference is the aging of whisky and rum is in a barrel or cask rather than a bottle. The Vint Futures and Casks I fund gives investors the best of both worlds, with a target composition of 70% wine futures and 30% spirits casks and a projected hold time of five to six years. Get wine and whisky exposure through the Vint Futures and Casks I Fund. Knowledge Is Power Vint should know a thing or two about fine wine and aged whisky. The company has been around since 2019, offering equity products to investors who want exposure to these luxury asset classes. It also operates the Vint marketplace which sells fine wines and rare spirits to collectors, consumers and merchants. The marketplace was created to give investors the best exit price for Vint investment assets all the while mitigating investment fees. At last check, the Vint marketplace had over $70 million in assets and hundreds of customers. Vint also has performance to back it up – the company has returned capital from 14 deals resulting in an average realized net IRR of 28.7%. Fine wine and rare spirits investing has long been the domain of a select few. Vint is changing that by giving more investors access to what has the potential for long-term appreciation. Now that’s something to cheer about. Use the Vint platform to invest for as little as $2500. Benzinga is a leading financial media and data provider, known for delivering accurate, timely, and actionable financial information to empower investors and traders. This post contains sponsored content. This content is for informational purposes only and not intended to be investing advice. Contact Details Benzinga +1 877-440-9464 info@benzinga.com Company Website http://www.benzinga.com

January 30, 2024 08:00 AM Eastern Standard Time

Bitget Wallet Partners with Morph, Becoming the First Web3 Wallet to Support Morph Testnet

Bitget

Morph, the Layer 2 user-centric Blockchain, has officially launched its testnet beta and will be embarking on an exciting cooperation with Bitget Wallet, allowing Bitget Wallet users to connect to the Morph testnet on both the mobile and browser versions of Bitget Wallet, and explore Morph testnet bridge. Morph plans to launch its mainnet Beta version in the second quarter of this year, with Bitget Wallet being among the first wallets to support network integration and further development of the Morph ecosystem. From January 30th to February 15th, Bitget Wallet will be holding a Morph testnet launch event, rewarding limited edition commemorative Morphy badges to all participants on the Morph testnet as a token of recognition for their loyalty and dedication to the Morph network. Further, 500 Morphy badge holders will also be randomly selected to share in an additional 5,000 GASU airdrop from Bitget Wallet. Morph is a transparent, community-driven Layer-2 solution. Combining the best of OP and ZK rollups, it offers unmatched scalability and security, aiming to lay the foundations for a consumer-oriented ecosystem featuring value-driven DApps. Leveraging unique features including a Decentralized Sequencer Network, Responsive Validity Proof (RVP) system, and modular design, Morph is set to deliver efficient and flexible scaling while preserving the initial security, availability, and compatibility of the Ethereum network. In December 2023, Bitget completed a multimillion-dollar investment in Morph. Bitget Wallet currently supports over 100 mainnets and allows users to effortlessly integrate hundreds of EVM-compatible chains with a simple one-click customization feature. This diverse network array not only provides greater accessibility for users, it also introduces a cornucopia of novel assets and opportunities. Dedicated to embracing each new asset and market trend, Bitget Wallet will continue upgrading its product suite in line with new innovations and developments in the market, providing leading on-chain asset services for all its users. About Bitget Wallet Bitget Wallet stands as Asia's largest and global frontrunner among all-in-one Web3 multi-chain wallets. We offer a comprehensive range of on-chain products and DeFi services to our users, including wallet functionality, Swap feature, NFT trading, DApp browsing, and more. With a 5-year legacy, Bitget Wallet has garnered acclaim from over 15 million users worldwide and has secured partnerships with prominent industry leaders including Bitcoin, Ethereum, TRON, BNB Chain, Solana, Base, and others. This success stems from our commitment to consistently delivering secure and convenient products and services. For more information, visit: https://linktr.ee/bitgetwallet Contact Details Bitget Rachel Cheung media@bitget.com Company Website https://www.bitget.com/

January 30, 2024 06:43 AM Eastern Standard Time

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Bitget Lists API3 (API3) in Innovation Zone and DeFi Zone

Bitget

Bitget, the world's leading cryptocurrency exchange and Web3 company, announces the listing of API3 (API3) in Innovation Zone and DeFi Zone, reinforcing its commitment to providing cutting-edge opportunities to users. This strategic move signals Bitget’s dedication to supporting the development of diverse blockchains and ecosystems while enhancing its market offerings. API3 addresses a critical challenge in the blockchain industry: the reliable and seamless access of smart contracts to essential real-world data. The platform aims to facilitate the creation, management, and monetization of decentralized versions of APIs on a large scale. As blockchain technology continues to permeate various sectors, ranging from decentralized finance to supply chain management, the necessity for smart contracts to deliver timely and dependable real-world data has become increasingly paramount. With its unveiling in September 2020, the whitepaper for API3 shed light on a fundamental issue plaguing current APIs: connectivity. Presently, smart contracts lack a direct pathway to connect with APIs for the latest data, leading to an upsurge in the demand for oracles. Gracy Chen, Managing Director of Bitget states, "Bitget seeks a good way to support the development of different blockchains and ecosystems. This project showcases the innovative potential and support for the crypto ecosystem, aligning with our commitment to offering our users access to cutting-edge projects. We aim to create a Spot Market with rich choices and excellent quality projects." In recent years, Bitget has consistently broadened its market reach, excelling in both spot and derivatives trading among centralized exchanges. The platform remains steadfast in its efforts to foster investment opportunities, aiming to enrich the diversity of digital assets in its spot market. Notably, in 2023 alone, Bitget introduced over 350 new listings, demonstrating its dedication to expanding user choices. Moreover, Bitget Wallet accommodates over 100 mainnets and supports a vast array of 250,000+ tokens. Through its on-chain trading function, Bitget Swap, users can seamlessly engage in cross-chain trading across nearly 30 mainnets. For more information, please visit: https://www.bitget.com/support/articles/12560603804648 About Bitget Established in 2018, Bitget is the world's leading cryptocurrency exchange and Web3 company. Serving over 20 million users in 100+ countries and regions, the Bitget exchange is committed to helping users trade smarter with its pioneering copy trading feature and other trading solutions. Formerly known as BitKeep, Bitget Wallet is a world-class multi-chain crypto wallet that offers an array of comprehensive Web3 solutions and features including wallet functionality, swap, NFT Marketplace, DApp browser, and more. Bitget inspires individuals to embrace crypto through collaborations with credible partners, including legendary Argentinian footballer Lionel Messi and official eSports events organizer PGL. For more information, visit: Website | Twitter | Telegram | LinkedIn | Discord | Bitget Wallet Contact Details Bitget Rachel Cheung media@bitget.com Company Website https://www.bitget.com/

January 30, 2024 06:38 AM Eastern Standard Time

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News Release

Unveiling Mike Johnson's Vision for the Evolving Cryptocurrency Era in Finance

ZEX GLOBAL MEDIA

The financial landscape is undergoing a substantial metamorphosis, characterized by a growing exodus of individuals diverting their capital from conventional banks towards the realm of cryptocurrencies. This phenomenon has triggered a range of reactions from banking institutions, with some appearing to discourage this shift. This article explores the underlying reasons behind these reactions, bridging the complexities of traditional banking and the allure of digital currencies. Furthermore, it incorporates insights from Mike Johnson, an accomplished investor and former banker who has made a remarkable transition into a fervent advocate for the world of cryptocurrencies. Traditional Banking at a Crossroads: Navigating Challenges Amid the surge in Cryptocurrencies The cornerstone of traditional banking is built upon established models like the fractional reserve banking system, in which client deposits function as a lever for lending and investment activities. However, this system faces challenges when significant sums of money flow into the volatile realm of cryptocurrencies. The redirection of said funds doesn’t just diminish the lending capacity of banks but also presents potential threats to liquidity and their overall financial stability. Banks' concerns extend beyond the present financial repercussions, encompassing the shadow of instability stemming from a widescale shift toward investments in cryptocurrency. The cagey or repressive stance taken by financial institutions in this context can be perceived as a measured strategy for risk management, serving the both the purpose of protecting individual investors, as well as the financial institution. Mike Johnson's Perspective: Shifting from a Banker to Becoming a Crypto Advocate" Providing a unique viewpoint on the ever-shifting financial terrain, Mike Johnson, a former banker-turned-passionate advocate for cryptocurrencies, illuminates the profound shift taking place. Johnson contends that embracing cryptocurrencies goes beyond mere financial decision-making; it signifies a cultural transformation. He passionately states, "It's about seizing ownership of your financial future." In his view, traditional banks, while offering stability, exemplify a system which is intrinsically inflexible and generally slow to embrace innovation. According to Hyman, not only do cryptocurrencies promise significant gains, but they also represent a more flexible and inclusive financial system. While confirming the intrinsic risks that correspond with cryptocurrencies, he maintains that said risks are an essential part of their transformative appeal. He recognizes the tentative stance adopted by banks as a characteristic defensive tactic, but encourages an approach that is more forward-thinking, proposing that banks explore the integration of cryptocurrency based solutions as part of their services. Striking a Balance Between apprehension and Opportunity This prudent approach taken by financial institutions, as previously emphasized, may lead to behavior that might appear to discourage the movement of funds into the cryptocurrency realm. These actions can take the form of increased risk advisories, the implementation of more stringent regulations on transfers, and even categorical measures of discouragement. At this juncture where conventional banking meets the expanding cryptocurrency landscape, the fine equilibrium between caution and the myriad of possibilities that cryptocurrencies offer become all the more apparent. Drawing Insights: Balancing the advancing Financial Landscape The shift from conventional banking to the world of cryptocurrencies represents a significant upheaval in the world of finance. As banks proactively adopt measures to protect their own interests as well as the interests of their clients, these actions form a crucial part of a larger equilibrium within a constantly changing financial environment. Mike Johnson's perspectives serve as a passionate call to remember the importance of adopting a balanced stance. This approach recognizes the stability that traditional banking offers, while also embracing the inherent transformative potential of cryptocurrencies. In an environment where the financial landscape constantly morphs, the strategies that financial institutions and investors rely on must remain adaptable, each navigating through the ever-changing and evolving landscape with foresight and agility. Contact Details Revenue Center Pro Tony Allen support@revenuecenterpro.email

January 30, 2024 02:40 AM Eastern Standard Time

News Release

Unveiling Mike Johnson's Vision for the Evolving Cryptocurrency Era in Finance

ZEX GLOBAL MEDIA

The financial landscape is undergoing a substantial metamorphosis, characterized by a growing exodus of individuals diverting their capital from conventional banks towards the realm of cryptocurrencies. This phenomenon has triggered a range of reactions from banking institutions, with some appearing to discourage this shift. This article explores the underlying reasons behind these reactions, bridging the complexities of traditional banking and the allure of digital currencies. Furthermore, it incorporates insights from Mike Johnson, an accomplished investor and former banker who has made a remarkable transition into a fervent advocate for the world of cryptocurrencies. Traditional Banking at a Crossroads: Navigating Challenges Amid the surge in Cryptocurrencies The cornerstone of traditional banking is built upon established models like the fractional reserve banking system, in which client deposits function as a lever for lending and investment activities. However, this system faces challenges when significant sums of money flow into the volatile realm of cryptocurrencies. The redirection of said funds doesn’t just diminish the lending capacity of banks but also presents potential threats to liquidity and their overall financial stability. Banks' concerns extend beyond the present financial repercussions, encompassing the shadow of instability stemming from a widescale shift toward investments in cryptocurrency. The cagey or repressive stance taken by financial institutions in this context can be perceived as a measured strategy for risk management, serving the both the purpose of protecting individual investors, as well as the financial institution. Mike Johnson's Perspective: Shifting from a Banker to Becoming a Crypto Advocate" Providing a unique viewpoint on the ever-shifting financial terrain, Mike Johnson, a former banker-turned-passionate advocate for cryptocurrencies, illuminates the profound shift taking place. Johnson contends that embracing cryptocurrencies goes beyond mere financial decision-making; it signifies a cultural transformation. He passionately states, "It's about seizing ownership of your financial future." In his view, traditional banks, while offering stability, exemplify a system which is intrinsically inflexible and generally slow to embrace innovation. According to Hyman, not only do cryptocurrencies promise significant gains, but they also represent a more flexible and inclusive financial system. While confirming the intrinsic risks that correspond with cryptocurrencies, he maintains that said risks are an essential part of their transformative appeal. He recognizes the tentative stance adopted by banks as a characteristic defensive tactic, but encourages an approach that is more forward-thinking, proposing that banks explore the integration of cryptocurrency based solutions as part of their services. Striking a Balance Between apprehension and Opportunity This prudent approach taken by financial institutions, as previously emphasized, may lead to behavior that might appear to discourage the movement of funds into the cryptocurrency realm. These actions can take the form of increased risk advisories, the implementation of more stringent regulations on transfers, and even categorical measures of discouragement. At this juncture where conventional banking meets the expanding cryptocurrency landscape, the fine equilibrium between caution and the myriad of possibilities that cryptocurrencies offer become all the more apparent. Drawing Insights: Balancing the advancing Financial Landscape The shift from conventional banking to the world of cryptocurrencies represents a significant upheaval in the world of finance. As banks proactively adopt measures to protect their own interests as well as the interests of their clients, these actions form a crucial part of a larger equilibrium within a constantly changing financial environment. Mike Johnson's perspectives serve as a passionate call to remember the importance of adopting a balanced stance. This approach recognizes the stability that traditional banking offers, while also embracing the inherent transformative potential of cryptocurrencies. In an environment where the financial landscape constantly morphs, the strategies that financial institutions and investors rely on must remain adaptable, each navigating through the ever-changing and evolving landscape with foresight and agility. Contact Details Revenue Center Pro Revenue Center Pro support@revenuecenterpro.email

January 30, 2024 01:22 AM Eastern Standard Time

Uno Pizzeria and Grill Releases New Mardi Gras Inspired Menu

UNO Pizzeria & Grill

Uno Pizzeria and Grill, the iconic restaurant brand and the birthplace of deep dish pizza, has introduced a new limited-time-only menu that features the flavors of New Orleans and Mardi Gras. With Fat Tuesday on February 13 th this year, the company wanted to release the menu in advance of the celebration of Mardi Gras to give guests the opportunity to try the flavorful new items over an extended period of time. The menu features UNO's spin on classic New Orleans dishes as well as a few completely new tasty creations. Items featured on the menu include: Big Easy Gumbo – A bowl of chicken, shrimp, and andouille sausage gumbo with rice, vegetables and classic Cajun seasoning. Cheesy Grits and Shrimp Appetizer – Shrimp sautéed with bacon, onion and a housemade Makers Mark BBQ sauce served over cheesy grits. Seasoned Fried Shrimp Appetizer – Tender shrimp dusted in seasoned flour (with a tiny kick) and deep fried to a golden brown. Served with a housemade remoulade sauce. New Orleans Pasta – A delicious combination of chicken, shrimp, andouille sausage and seasoned plum tomatoes sautéed with garlic, celery, and UNOs spicy alfredo sauce. Tossed with rigatoni. Mike’s Hot Honey Chicken and Cornbread – In-house baked cornbread topped with crispy chicken tenders and drizzled with Mike’s Hot Honey. Served with maple aioli. A hot new collab. Cajun Ribeye and Grilled Shrimp – A 10oz. Choice ribeye grilled to order with jazzy Cajun seasoning and served with a skewer of basil-marinated shrimp. Served with two sides. Jambalaya Deep Dish Pizza – A buttery deep dish dough filled with bayou-seasoned shrimp, chicken, andouille sausage, seasoned plum tomatoes, caramelized onions and celery. Topped with freshly grated mozzarella, cheddar and asiago cheeses. Andouille Sausage Bayou Thin Crust Pizza – Housemade dough and marinara sauce topped with andouille sausage, caramelized onions, mozzarella, ricotta and banana peppers. “This new menu offers our guests a fun and flavorful food experience. Having lived in New Orleans for a portion of my life, I am keenly aware that New Orleans and Mardi Gras celebrate community, food and fun. These are qualities that are alive and well in all of our UNOs locations every day.” stated CEO Erik Frederick. He continued, “We want to give our guests menu options that are a bit different than what you would normally see at UNOs, or any other restaurants for that matter. All of these items really kick up the flavor and spice a few notches. As they say in New Orleans “Laissez les bons temps rouler!” which means “Let the good time roll!” To celebrate the release of the menu, UNOs is offering a BOGO 50% off deal on the Mardi Gras menu items from January 31 st to February 4 th. Offer is valid on all food menu items (drinks excluded from offer). The offer is valid for dine-in and participation may vary by location. The limited-time-only Mardi Gras menu is available at most UNOs locations and is scheduled to run into April 2024. About UNO Pizzeria & Grill Based in Boston, Massachusetts, Uno Restaurant Holdings Corporation includes approximately 80 company-owned and franchised UNO Pizzeria & Grill restaurants located in 18 states, and the District of Columbia, India, and Saudi Arabia. UNO is all about connecting people over pizza – from its famous Chicago Deep Dish, which UNO invented in 1943, to its Chicago Thin Crust, to its gluten-free and vegan pizzas. Contact Details Chris Dellamarggio +1 339-613-7641 cdellamarggio@unos.com Company Website https://www.unos.com/

January 29, 2024 11:11 AM Eastern Standard Time

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News Release

Allied Signs a 3-Year Sales Agreement to Provide its Colombian Grown Cannabis to the United Kingdom

Allied Corp.

Kelowna, BC, Canada – TheNewswire - January 29, 2024 - Allied Corp. ("Allied" or the “Company”) ( OTC:ALID ) is pleased to announce that it has signed a three-year sales and distribution agreement for the UK market. This comes following the expansion of Allied’s commercial team in 2023 and the recent announcement of strategic channel partnerships to enable EU-GMP manufactured products to be distributed across Europe. According to Prohibition Partner’s 2023 European Cannabis Report, the UK market is set to become the second largest medical cannabis market in Europe after Germany. “ This achievement is the result of the company’s dedication to expanding its commercial efforts in 2023 and marks a significant milestone as we are set to enter one of the most promising European markets.” says Juba Hadid, VP of Global Sales. The sales and distribution agreement was executed between Allied, its EU-GMP Manufacturing channel partner and a licensed medical cannabis distribution company located in the UK. Under this agreement, Allied will provide, through its EU-GMP manufacturing partner, Colombian grown medical cannabis for a duration of 3 years from the date of signing with the option to renew for subsequent years. This agreement details the provisions of the supply partnership into the territory, including specified minimum monthly order quantities and a yearly volume commitment. About Allied Corp. – CLICK HERE Allied Corp. is an international cannabis company with its main production center in Colombia. It is one of the few companies that has exported from Colombia internationally and was the first company to export commercial cannabis flower from Colombia. By leveraging the Colombian advantages and its Canadian cannabis cultivation expertise, Allied offers consistent supply of premium cannabis product at scale and attractive prices, while meeting high quality standards, thus significantly de-risking its partners supply chain. Investor Relations: ir@allied.health 1-877-255-4337 Forward-Looking Statements: This press release contains “forward-looking information” within the meaning of applicable securities laws in Canada or the United States ( “forward-looking information”). Forward-looking information may relate to the Company’s future outlook and anticipated events, plans or results, and may include information regarding the Company’s objectives, goals, strategies, future revenue or performance and capital expenditures, and other information that is not historical information. Forward-looking information can often be identified by the use of terminology such as “believe,” “anticipate,” “plan,” “expect,” “pending,” “in process,” “intend,” “estimate,” “project,” “may,” “will,” “should,” “would,” “could,” “can,” the negatives thereof, variations thereon and similar expressions. The forward-looking information contained in this press release is based on the Company’s opinions, estimates and assumptions in light of management’s experience and perception of historical trends, current conditions and expected future developments, as well as other factors that management currently believes are appropriate and reasonable in the circumstances. Forward looking statements in this press release include the following: that Allied is leveraging the conditions in its Colombia grow operation and future Kelowna location to support its Research and Development efforts; that Allied is making important strides forward to position itself as a leader in the medical cannabis space, that Allied intends to make a series of proposed trademark and other intellectual property protection filings, as part of the Company’s Intellectual Property and Pharma Development (IP&PD) Strategy, statements respecting the joint development, manufacturing, and the introduction of TACTICAL RELIEF™ branded products. There can be no assurance that the underlying opinions, estimates and assumptions will prove to be correct. Risk factors that could cause actual results to differ materially from forward-looking information in this release include: the Company’s exposure to legal and regulatory risk; the effect of the legalization of adult-use cannabis in Canada and Colombia on the medical cannabis industry is unknown and may significantly and negatively affect the Company’s medical cannabis business; that the medical benefits, viability, safety, efficacy, dosing and social acceptance of cannabis are not as currently expected; that adverse changes or developments affecting the Company’s main or planned facilities may have an adverse effect on the Company; that the medical cannabis industry and market may not continue to exist or develop as anticipated or the Company may not be able to succeed in this market; risks related to completion of the greenhouse construction in Colombia, risks related to market competition; risks related to the proposed adult-use cannabis industry and market in Canada and Colombia including the Company’s ability to enter into or compete in such markets; that the Company has a limited operating history and a history of net losses and that it may not achieve or maintain profitability in the future; risks related to the Company’s current or proposed international operations; risks related to future third party strategic alliances or the expansion of currently existing relationships with third parties; that the Company may not be able to successfully identify and execute future acquisitions or dispositions or successfully manage the impacts of such transactions on its operations; risks inherent to the operation of an agricultural business; that the Company may be unable to attract, develop and retain key personnel; risks resulting from significant interruptions to the Company’s access to certain key inputs such as raw materials, electricity, water and other utilities; that the Company may be unable to transport its cannabis products to patients in a safe and efficient manner; risks related to recalls of the Company’s cannabis products or product liability or regulatory claims or actions involving the Company’s cannabis products; risks related to the Company’s reliance on pharmaceutical distributors; that the Company, or the cannabis industry more generally, may receive unfavorable publicity or become subject to negative consumer or investor perception; that certain events or developments in the cannabis industry more generally may impact the Company’s reputation or its relationships with customers or suppliers; that the Company may not be able to obtain adequate insurance coverage in respect of the risks that it faces, that the premiums for such insurance may not continue to be commercially justifiable or that there may be coverage limitations and other exclusions which may result in such insurance not being sufficient; that the Company may become subject to liability arising from fraudulent or illegal activity by its employees, contractors, consultants and others; that the Company may experience breaches of security at its facilities or losses as a result of the theft of its products; risks related to the Company’s information technology systems; that the Company may be unable to sustain its revenue growth and development; that the Company may be unable to expand its operations quickly enough to meet demand or manage its operations beyond their current scale; that the Company may be unable to secure adequate or reliable sources of necessary funding; risks related to, or associated with, the Company’s exposure to reporting requirements; risks related to conflicts of interest; risks related to fluctuations in foreign currency exchange rates; risks related to the Company’s potential exposure to greater-than-anticipated tax liabilities; risks related to the protection and enforcement of the Company’s intellectual property rights, or the intellectual property that it licenses from others; that the Company may become subject to allegations that it or its licensors are in violation of the intellectual property rights of third parties; that the Company may not realize the full benefit of the clinical trials or studies that it participates in; that the Company may not realize the full benefit of its licenses if the licensed material has less market appeal than expected and the licenses may not be profitable; as well as any other risks that may be further described in and the risk factors discussed in the Company's continuous disclosure including its Management's Discussion and Analysis sections in its Quarterly Reports on Form 10-Q, Annual Reports on Form 10-K and Current Reports on Form 8-K filed under the Company's profile at www.sec.gov. Although management has attempted to identify important risk factors that could cause actual results to differ materially from those contained in the forward-looking information in this presentation, there may be other risk factors not presently known to the Company or that the Company presently believes are not material that could also cause actual results or future events to differ materially from those expressed in such forward-looking information in this presentation. There can be no assurance that such information will prove to be accurate, as actual results and future events could differ materially from those anticipated in such information. Accordingly, readers and viewers should not place undue reliance on forward-looking information, which speaks only as of the date made. The forward-looking information contained in this release represents the Company’s expectations as of the date of this release or the date indicated, regardless of the time of delivery of the presentation. The Company disclaims any intention, obligation or undertaking to update or revise any forward-looking information, whether as a result of new information, future events or otherwise, except as required under applicable securities laws.

January 29, 2024 09:36 AM Eastern Standard Time

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