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Medica Group eyeing up "significant opportunity"

Medica Group PLC

Medica Group PLC (LSE:MGP) chief executive Dr Stuart Quin speaks to Proactive's Thomas Warner following the release of a 2022 trading update. He reveals more information about what he calls a "significant opportunity' for the Medica Group as it heads into another new year, and discusses where he believes the bulk of its growth will come from. Contact Details Proactive Proactive UK Ltd +44 20 7989 0813 uk@proactiveinvestors.com

January 20, 2023 07:05 AM Eastern Standard Time

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Prescriptions Generated Three Times More Frequently on POC Mediums: Doceree 2022 Annual Report

Doceree

Point-of-Care (POC) channels have changed the dynamics of how life sciences brands interact with healthcare professionals (HCPs) which has led to script generation to become three times on POC than on other online mediums, Doceree has revealed in its annual report – Doceree 360 (2022 Edition). Doceree, a global platform building unprecedented solutions for HCP programmatic messaging with proprietary data tools, today released its annual report, compiled post analysis of more than 250 POC campaigns run on its platform over the last year. To drive prescriptions, it is crucial for life sciences brands to target HCPs while they tend to their patients, which is only on point-of-care channels, concludes the report. Doceree has pioneered initiatives to evolve the POC ecosystem with insightful learnings for life sciences brand marketers and platforms. A few months prior to the report launch, the company’s Founder and CEO Harshit Jain, MD launched a book on the subject with the goal of preparing marketers and point-of-care platforms for the next way to effectively reach and engage clinicians through online platforms. “The POC landscape is in its nascent stage and is evolving at a fast pace,” Jain said. “There is apparently a lack of standardization owing to limited availability of data points and metrics at this stage. “We are attempting to fill this gap by diving into the multiple POC campaigns we have executed on our platform in the past year to deduce some insightful learnings for marketers to take cognisance of,” he continued. “It will empower them to embrace data-driven strategies and personalize HCP communications with a deep understanding of online behavior patterns of providers based on real-time campaigns.” The other key findings in the report are: HCPs spend an average of six hours out of an average 11-hour workday on EHR Script lift is 32% higher in trigger-based messaging Cost per HCP is 17% less on POC than on other mediums Doceree gauged more than 21 million impressions served to more than 600,000 HCPs on its over 70-partner POC channels. Campaigns of around 100 advertisers - comprising consumer healthcare and medical devices companies, life sciences brands, hospitals, and diagnostics - run on a blend of POC channels, consisting of EHR, eRx, telemedicine, EHR apps, were taken into account. Brand campaigns for more than 190 specialties, including Primary Care, Cardiology, Oncology, Hematology, Nephrology, Gynaecology and Pulmonology, were studied as part of the research for the report findings. View the complete report by visiting: https://doceree.com/in/reports/doceree-360-2022-edition/ About Doceree Doceree is a global platform building unprecedented solutions for healthcare professional (HCP) programmatic messaging with proprietary data tools. It facilitates messaging between life sciences brands and HCPs through an extensive global network of digital endemic and point-of-care platforms to programmatically deliver personalized communications to HCPs and transparent marketing campaign metrics at scale. To learn more, visit doceree.com. Contact Details Kite Hill PR +91 70420 89805 doceree@kitehillpr.com Company Website https://doceree.com/us/

January 19, 2023 11:20 AM Eastern Standard Time

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Oliver Inc. Acquires Tap Packaging + Design

Oliver Inc.

Oliver Inc. (“Oliver”) is pleased to announce that it has acquired Tap Packaging + Design. Tap Packaging is a leading manufacturer of custom folding cartons, serving customers in food and beverage, beauty, confection, health and wellness, and consumer goods markets. Based in Cleveland, Ohio, Tap Packaging will continue delivering design-forward packaging solutions from its current location. This partnership will enable Oliver to expand its product offerings and strengthen its position as the nation’s largest independent specialty packaging supplier. “We are thrilled to welcome the Tap team to the Oliver family,” said Dan Rodenbush, President/CEO of Oliver Inc. "Their diverse range of capabilities will allow us to expand our product offerings and enhance our overall service for our customers.” “Oliver and Tap Packaging share similar core values, and both companies have a passion for providing an exceptional customer experience,” added David Chilcote, Chairman of Tap Packaging. “Partnering with Oliver increases our capacity, provides redundancy, and allows us to better leverage our combined scale to offer enhanced solutions for our customers.” Oliver has made significant investments in modern equipment, facilities, and people since 2016. The Tap Packaging transaction will represent Oliver’s fifth strategic acquisition and aligns with the company’s vision to build a leading provider of innovative, specialty packaging solutions. The transaction closed on January 18, 2023. To learn more about Oliver, please visit www.oliverinc.com. About Oliver Oliver Inc. is a leading provider of highly customized, quick-turnaround, specialty packaging solutions. Known for its white-glove approach to customer service, the company provides a turnkey platform from design to fulfillment, simplifying complex requirements with consistent on-time, on-budget, ultra-high-quality products and services. About Tap Packaging + Design Since 1906, Tap Packaging + Design has been committed to enhancing their customers’ image by providing high-quality packaging and presentation products. The company’s success can be attributed to the creative craftsmanship of their dedicated workforce, and their sincere desire to partner with their customers and suppliers. Contact Details Oliver Inc. Doug Doroh +1 631-234-1400 ddoroh@oliverinc.com Company Website https://www.oliverinc.com/

January 19, 2023 09:20 AM Eastern Standard Time

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Acurx Is Vying for Standard of Care in Treating Primary and Recurrent C. diff

Acurx Pharmaceuticals Inc

By Faith Ashmore, Benzinga C. diff is a life-threatening bacterial infection that causes diarrhea and colitis, which is the inflammation of the colon. Approximately 600,000 are diagnosed with C. diff each year in the United States and it causes approximately 55 deaths a day. In the elderly population, 1 in 11 individuals over the age of 65 die within the month after being infected. The infection has a high recurrent rate, about 1 in 6 patients who get C. diff will get it again within 2-8 weeks. The current treatment for C. diff is vancomycin, an antibiotic that is typically prescribed for serious pathogenic infections. While the drug is safe and has proven successful, the antibiotic has been on the market for 65 years and its effectiveness has been steadily declining as more and more bacteria have become resistant to it, consistent with the path of virtually all other antibiotics over time. Understanding the need for a new antibiotic to treat C. diff, Acurx Pharmaceuticals ( Nasdaq: ACXP ) is developing ibezapolstat, a novel first-in-class antibiotic currently in mid-stage clinical testing. It has been given Fast Track designation by the FDA and has been designated by the FDA as a Qualified Infectious Disease Product (QIDP), which grants priority review by the FDA and provides an additional five years of market exclusivity upon approval. The CDC acknowledges an ”urgent need” for new antibiotics to treat C. diff. During the Phase 2a clinical trial, 100% of the first 10 patients were clinically cured of C. diff and did not have a recurrent infection within a 28-day period after the end of treatment with no safety concerns. Because of these strong results, the Scientific Advisory Board recommended that the trial be stopped early for success. The current standard of care, vancomycin, has an average clinical cure rate of 80% with a 30% chance of recurrent infection. In comparison, ibezapolstat would be a far more suitable drug with a higher success rate if current data holds in late-stage development. Acurx is expecting similarly strong results for their Phase 2b clinical trial. The company is expected to release topline results by mid-2023 if the FDA agrees with the company’s plan for an interim analysis. If the trials continue to be a success and ibezapolstat demonstrates statistical noninferiority compared to vancomycin in curing primary C. diff, it could win FDA approval and be used as first line therapy. But of equal, or even greater, importance are the results being shown in preventing recurrence -- the major cause of C. diff morbidity and mortality, and the principal contributor to C. diff’s $4.5 billion annual cost to the US healthcare system. Being able to reduce or eliminate recurrence would be a game-changing development in treating an infection that affects so many individuals, especially amid rising bacterial resistance to vancomycin. Ibezapolstat’s potential game-changing status would be further assured if it scores well in two exploratory endpoints in the current Phase 2b trial – the number of disease-free patients at days 60 and 90 (two time points not included on any product labeled for C. diff.) and if it continues to demonstrate restoration of the healthy microbiome of C. diff patients during the treatment process. Click here for more information about Acurx. About Acurx Pharmaceuticals, Inc. Acurx Pharmaceuticals is a clinical stage biopharmaceutical company focused on developing an entirely new class of antibiotics for difficult to treat infections. The Company's approach is to develop antibiotic candidates that target the DNA polymerase IIIC enzyme and its R&D pipeline includes antibiotic product candidates that target Gram-positive bacteria, including Clostridioides difficile, methicillin-resistant Staphylococcus aureus (MRSA), vancomycin resistant Enterococcus (VRE) and drug-resistant Streptococcus pneumoniae (DRSP). To learn more about Acurx Pharmaceuticals and its product pipeline, please visit www.acurxpharma.com This post contains sponsored advertising content. This content is for informational purposes only and is not intended to be investing advice. Photo by Mark Fletcher-Brown on Unsplash Contact Details Acurx Pharmaceuticals, Inc. David P. Luci, President & CEO +1 917-533-1469 davidluci@acurxpharma.com Company Website https://www.acurxpharma.com/

January 19, 2023 09:00 AM Eastern Standard Time

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Centre for Neuro Skills Offers “Continued Care Program” for Patients with Brain Injuries

Centre for Neuro Skills

Approximately 3 million Americans are affected by an acquired brain injury every year. Traumatic brain injury (TBI) and stroke are the leading causes of acquired brain injury. More than 5 million Americans live with disabilities due to a TBI and often require rehabilitative care. Centre for Neuro Skills (CNS), a leader in brain injury rehabilitation services, today announced the offering of its Continued Care Program, which will provide all-encompassing care after active rehabilitation therapy for patients recovering from a brain injury or stroke by offering assisted living, residential and supported living options while empowering patients to regain motor skills so they can achieve the highest level of independence possible. The new facets of the program include: Assisted Living Residential Residential Care Supported Living Enrichment Center Brain injury rehabilitation has proven to be effective, returning a substantial number of people to productive and satisfying lives, but some individuals who experience brain injury or stroke cannot recover full independence due to disturbances in cognition, mood and behavior. These consequences of brain injury and stroke can lead to isolation, depression and re-hospitalization as well as caregiver stress and burnout. Continued Care Programs can meet the long-term needs of individuals with chronic disabilities, providing specialized care that decreases risk for re-hospitalization, promoting life satisfaction and quality of life and reducing life-time costs. “Centre for Neuro Skills’ Continued Care program introduces patients to new experiences, provides them access to valuable community resources and challenges them to adapt and grow beyond their current limitations,” said Dr. Mark Ashley, CEO and founder of Centre for Neuro Skills. “CNS’ experienced staff are committed to the overall well-being of each patient, empowering patients to enjoy dignified, productive lives and dedicated to helping them achieve the best possible quality of life.” Assisted Living Residential CNS Assisted Living Residential patients typically transition from the Inpatient Residential program. In Assisted Living Residential, patients: Live in a CNS residence close to the clinic Attend the CNS Enrichment Center May or may not still receive some therapies Receive transportation to and from CNS-sponsored activities Residential Care In residential settings, CNS can provide full-time or part-time care, helping patients to practice and strengthen skills obtained in its clinical facilities while residing in a secure, home-like CNS residence nearby. Each day, patients are transported between the CNS residence and clinic by its certified Transportation Services Department. A broad range of skills are taught and modeled, including, but not limited to: Safety at home and in the community Self-care Money and time management Proper medication use Social activities Behavior management Supported Living CNS’ Supported Living focuses on maintaining the patient outcomes achieved in active therapy. Patients receiving this care may have transitioned from Inpatient Residential, Day Treatment or Assisted Living Residential treatment options. Patients in Supported Living have schedules consisting of a broad range of personalized CNS services tailored to their ongoing needs. Enrichment Center CNS’ Assisted Living Residential or Supported Living patients can use the Enrichment Center, a space in the clinic that offers scheduled, structured and age-appropriate activities for patients to maintain the outcomes achieved in active therapy. Activities are centered around the patient’s personal interest and capabilities while focusing on therapeutic endeavors, engagement opportunities and skill building. *** About Centre for Neuro Skills Centre for Neuro Skills is an experienced and respected world leader in providing intensive rehabilitation and medical programs for those recovering from all types of brain injury. CNS covers a full spectrum of advanced care from residential and assisted living to outpatient/day treatment. Founded by Dr. Mark Ashley in 1980, CNS has seven locations in California and Texas. For more information about Centre for Neuro Skills, visit: www.neuroskills.com, Facebook, Twitter, LinkedIn, YouTube. Media, please note: Visual assets, including photos, are available. To request an interview with CNS leadership or clinical staff, please contact Robin Carr at 415.766.0927 or CNS@landispr.com. # # # Contact Details Landis Communications Inc. Robin Carr +1 415-766-0927 cns@landispr.com Company Website https://www.neuroskills.com/

January 18, 2023 07:10 AM Pacific Standard Time

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GROUNDWORK BIOAG EXPANDS NORTH AMERICAN TEAM TO SUPPORT FARMER DEMAND FOR MYCORRHIZAL INOCULANTS

Groundwork BioAg

Groundwork BioAg announced today that industry leader Andrew Duff has joined as General Manager - North America. Duff’s more than 20 years of experience in biostimulants, seed technology and U.S. crop production will help the company accelerate the adoption of its Rootella mycorrhizal inoculants and meet demand for biological solutions in mainstream crops, such as corn, soybean and cotton. “The demand from mainstream growers for more biological and regenerative solutions continues to increase,” said Hanan Dor, Chief Commercial Officer at Groundwork BioAg. “The United States remains an important growth market for us and essential to producing more sustainable food for the world. As a well-respected leader in agriculture and a life-long farmer, we believe Andrew is the right person to help us to expand our strategic partnerships, meet grower demand for our Rootella product portfolio and accelerate our carbon sequestration projects to help all farmers tap into existing carbon markets.” In this newly created role, Duff will lead the company’s existing operations established in 2016 and ensure a direct line of communication with North American distribution partners and growers, following another consecutive year of growth for Groundwork BioAg. “I am incredibly excited to join Groundwork BioAg at such a pivotal time in agriculture when many farmers and industry partners are adopting new solutions that address climate concerns and sustainability goals,” said Duff. “Groundwork BioAg is on the forefront of climate-smart agriculture and is bringing products to the farm that improve profitability today and for generations to come.” Growing up on a farm in the Mississippi Delta, Duff brings a wealth of knowledge and in-depth experience in agriculture spanning across distribution, manufacturing and production with an expertise in major crop inputs. Previously, Duff led global strategy for biostimulants at Verdesian Life Sciences. In addition, he served in leadership roles at Pinnacle Agriculture and Monsanto. He attended business school at the University of Mississippi and earned a law degree and MBA from Mississippi College. Duff is currently based in Southaven, Mississippi. About Groundwork BioAg Groundwork BioAg, a global bioagriculture company, leverages the natural power of mycorrhizal fungi to improve the productivity, sustainability and profitability of commercial agriculture and expand regenerative agriculture practices. Groundwork BioAg is the first to use innovative techniques to solve challenges inherent in high-volume mycorrhizal inoculant production. We will not rest until every hectare of arable land is protected by mycorrhizae and every farmer benefits from higher crop yields while preserving our soils. For more information, visit www.groundworkbioag.com. Contact Details AgTech PR for Groundwork BioAg Nicole Prenger nicole@agtechpr.com Company Website https://www.groundworkbioag.com

January 18, 2023 08:00 AM Central Standard Time

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PDG Announces New Vision on Sales Transformation Solutions 
for Life Sciences

PDG

Performance Development Group (PDG), a leader in providing business performance solutions, announces that it is “Bringing Success to Life” with an expanded sales performance solution set specifically for commercial organizations within life sciences. The new solution includes leadership development (coaching and accountability excellence), field force optimization, and business execution (leading and lagging metrics for success). Sales performance is a critical capability and one of the highest priorities for pharmaceutical, biotech, and medical device organizations. The dynamics and unpredictability of these industries are very high, and the margin for error is thinner than ever before. The evolving marketplace is highly regulated and complex, competition is fierce, and sales teams are constantly expected to adapt with limited information. As a result, the industry needs a dedicated performance solutions partner who understands these challenges across therapeutic areas and can clear a path to help them compete. “The sales organization within life sciences requires a focus like no other. We have seen complexity over the years and feel that this new business focus will allow us to deliver unique insights into the skills necessary to succeed like nobody else can,” said Sean Frontz, Global Practice Leader, Sales Performance, PDG. PDG has a long tradition of delivering business performance solutions to life science organizations. With this new business focus, PDG brings a team of experienced industry experts who understand how to shape solutions that are specific to each organization’s business goals. “With PDG’s increased focus and expertise on improving sales performance for life sciences organizations, we now have a unique ability and perspective to help our life sciences clients navigate ever-changing market dynamics and enable commercial teams to achieve and exceed their goals,” said Dave Manning, Founder and Managing Partner, of PDG. About PDG Since 2002, PDG has been helping the world’s leading life science organizations reach new heights in sales performance. PDG is laser-focused on driving measurable business results for business execution, sales transformation, leadership development, onboarding, employee engagement, and change management. To learn more, visit www.performdev.com Contact Details Performance Development Group Mercy Ehrler +1 610-854-4400 mehrler@performdev.com

January 18, 2023 09:00 AM Eastern Standard Time

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Poolbeg Pharma announces expansion of POLB 001 into oncology

Poolbeg Pharma PLC

Poolbeg Pharma PLC (AIM:POLB, OTCQB:POLBF) CEO Jeremy Skillington speaks to Proactive's Thomas Warner after announcing that the company has submitted a patent application for the use of POLB 001 in a new oncological indication. Skillington explains the reasons for the strategic expansion and reveals more about his vision for the molecule in the long term. Contact Details Proactive UK Ltd +44 20 7989 0813 uk@proactiveinvestors.com

January 18, 2023 08:10 AM Eastern Standard Time

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Sharps Technology Is Commercializing The Future Of Specialty Syringe Systems For The Healthcare Industry Through Its Next-Gen Polymer-Based Products

Sharps Technology Inc.

By David Willey, Benzinga Sharps Technology, Inc. (NASDAQ: STSS) recently announced that the Company will be commercializing cutting-edge prefillable syringe system products to provide new solutions to customers in the healthcare and pharmaceutical market. Sharps is advancing its product strategy with a transformative partnership with Nephron Pharmaceuticals that was announced in November 2022, and will co-manufacture its specialized systems at Nephron’s facility in South Carolina starting in 2023. Over the last 20 years, the pharmaceutical syringe operational model has shifted from the use of glass vials and bulk disposable syringes to next-generation prefillable syringes, increasing prefillables from 15% to 85% share. This has contributed to market expectations of $15.7 Billion in revenue for 2030 from $5.6 Billion reported in 2020 for prefillables. Potential customers and companies in the space include syringe system manufacturers such as Becton Dickson and Co. (NYSE: BDX), Cardinal Health (NYSE: CAH),, and Terumo Corporation (OTC: TRUMY). Sharps’ specialty polymer-based syringe systems are in significant demand and the company will serve healthcare and pharmaceutical customers that recognize the advantages of non-glass products. Prefillable or ready-to-use syringes drive down the total cost of ownership for pharmaceutical companies by simplifying the supply chain and reducing product waste. Key advantages of prefillable syringe systems address contamination issues for the broader healthcare market, improving drug shelf life while reducing unnecessary packaging, and providing best-in-class solutions to get drugs to patients more efficiently. Through its recent product launch announcement, Sharps is addressing multiple problems in the syringe system market by modernizing the prefillable space with its polymer-based product line. The Company has developed a high-quality alternative solution to glass syringes through the use of inert polymers such as Cyclic Olefin Polymer (COP) and Cyclic Olefin Copolymer (COC), which offers a high-quality solution as compared to traditional glass syringe systems. These polymer syringes have many of the same characteristics as current pharmaceutical glass designs to support long-term drug stability and increase shelf life for customers in the pharmaceutical segment. Polymer syringes can also be made into custom configurations, which function to eliminate breakage, minimize dead space, reduce contamination, and support the development of custom devices including autoinjectors. Sharps is also making a silicone-free prefillable product that addresses silicone interaction issues for the broader healthcare market. Currently, syringes are commonly made with medical-grade silicone, but utilizing siliconeand can result in drug contamination, adding a need for costly inspections every time syringes are filled. Sharps’ silicone-free solution removes the risk of interaction with biologics and eliminates the need for product inspections and potential product waste issues. Major Partnership with Nephron Pharmaceuticals Advances Manufacturing and Product Launches Though Sharps is currently a pre-revenue company, the Company is transitioning from a research and development company into commercial operations through a major partnership signed with Nephron Pharmaceuticals in November 2022. This collaboration will boost Sharps’ ability to reach out to the prefillable syringe market With manufacturing, sales and marketing solidified, the company is confident in its ability to execute on multiple revenue opportunities in the growing prefillable market. Initial demand will be supported by manufacturing capacity of 20+ million units, with additional capacities that can be scaled by 2025 with an additional 100 million units annually. Products will be manufactured utilizing state-of-the-art injection molding technologies with highly automated assembly lines. The products will be sterilized using an eco-friendly clean sterilization option easily adaptable for the pharmaceutical market. Sharps' systems will utilize ISO Standard Nest and Tubs that will be compatible with existing fill-finish technologies to provide a drop-in solution for the industry. Sharps believes this increased production capacity and distribution will allow it to fill a growing market that is looking for innovative prefillable solutions. The partnership is part of Nephron’s InjectEZ program to increase manufacturing out of its South Carolina operations. The use of Nephron’s manufacturing facility will advance Sharps’ development strategy by two years and the Company will get full access to Nephron’s lab capabilities, providing Sharps with the opportunity to continue to innovate for ongoing product development. Robert Hayes, Sharps Chief Executive Officer, recently commented: “Following years of research and development, Sharps is now in a position to commercialize and support the future of specialty syringe drug filling technology. The opportunity to advance our product and manufacturing strategy to include high-value prefillable syringe products will significantly accelerate our revenue growth for 2023 and beyond. The launch of these products could not come at a better time to support a market that is in demand for products produced in the USA that provide specialized solutions for customers that need options for their drug-filling operations. We look forward to providing updates as we commence manufacturing in South Carolina and introduce our new products to the market.” To learn more about Sharps Technology, visit its website. This article was originally published on Benzinga here. Sharps Technology is a medical device and pharmaceutical packaging company specializing in the development and manufacturing of innovative drug delivery systems. The company’s product lines focus on low waste and ultra-low waste syringe technologies that incorporate both passive and active safety features. These features protect front line healthcare workers from life-threatening needle stick injuries and protect the public from needle re-use. Sharps Technology has extensive expertise in specialized prefilled syringe systems and ready to use processing. The company has a manufacturing facility in Hungary and has partnered with Nephron Pharmaceuticals to expand its manufacturing capacity in the US. This post contains sponsored advertising content. This content is for informational purposes only and is not intended to be investing advice. Contact Details Adam Holdsworth- TraDigital IR adam@tradigitalir.com Company Website http://sharpstechnology.com/

January 17, 2023 10:00 AM Eastern Standard Time

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